She is best known for her roles as Monica Geller on the NBC sitcom Friends, Gale Weathers in the horror series Scream, and Jules Cobb in the ABC/TBS sitcom Cougar Town, for which she earned her first Golden Globe nomination. She owns a production company, called Coquette Productions, which was created by her then-husband David Arquette and her.Cox also worked as a director on her sitcom Cougar Town and the television film Talhotblond.
After graduating from Mountain Brook High School, Cox left for Mount Vernon College in Washington, DC, but did not complete her architecture course, opting instead to pursue a career in modeling and acting. Her early film roles include Masters of the Universe (1987), Cocoon: The Return (1988), and I'll Be Home for Christmas (1988).
Cox appeared in the 1984 music video for Bruce Springsteen's "Dancing in the Dark" as the young woman pulled onstage at the St. Her early television work includes a starring role in the short-lived television series, Misfits of Science (1985), and later in a recurring role as Lauren Miller, the girlfriend of Alex P. She played Jewel Jagger, the hard-as-nails assistant of Larry Burrows (James Belushi), in Mr. In 1994, shortly before the debut of the sitcom, Friends, Cox appeared with Jim Carrey in Ace Ventura: Pet Detective and as Jerry Seinfeld's girlfriend, Meryl, in the Seinfeld episode, "The Wife".
In 1995, she was cast in Toad the Wet Sprocket's music video, "Good Intentions". At first the most famous cast member of the new show, Cox joined fellow castmates Jennifer Aniston (Rachel Green), Lisa Kudrow (Phoebe Buffay), Matt Le Blanc (Joey Tribbiani), Matthew Perry (Chandler Bing) and David Schwimmer (Ross Geller) for what became her most famous role, lasting for 10 seasons until 2004.
According to the Guinness Book of World Records (2005), Cox (along with her female costars) became the highest-paid TV actress of all time, with her 1 million-per-episode paycheck for the final two seasons of Friends.
Between seasons five and six, Cox married David Arquette, and changed her name to Courteney Cox Arquette.
An in-joke reference to this is made in the beginning credits of the episode "The One After Vegas", where the rest of the cast has "Arquette" added to their names.
The dedication "For Courteney and David, who did get married" – a reference to Monica and Chandler's decision not to marry in the episode – appears during the fade out to the tag scene.
Cox also appeared in the high-profile Hollywood films, Scream (1996), Scream 2 (1997), and Scream 3 (2000), as reporter Gale Weathers.
She met her husband, David Arquette, who played her on-screen love interest Dwight "Dewey" Riley, while filming the first Scream film.